Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.54 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392254 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C19PRKD1TP53 | |
| SCHEMBL8870570 | 0.98 | CYP1A2 (0.96) | CYP1A2CYP3A4CYP2C19PRKD1TP53 | |
| SCHEMBL3143409 | 0.85 | CYP1A2 (0.74) | CYP1A2CYP3A4CYP2C19PRKD1ALDH1A1 | |
| SCHEMBL10793789 | 0.81 | ALDH1A1 (0.77) | CYP1A2CYP3A4CYP2C19PRKD1TP53 | |
| SCHEMBL30663248 | 0.81 | CYP3A4 (0.68) | CYP1A2CYP3A4CYP2C19PRKD1TP53 | |
| SCHEMBL10791718 | 0.80 | CYP1A2 (0.77) | CYP1A2CYP3A4CYP2C19PRKD1TP53 | |
| SCHEMBL10401284 | 0.80 | CYP3A4 (0.66) | CYP1A2CYP3A4CYP2C19PRKD1TP53 | |
| SCHEMBL11334978 | 0.79 | CYP1A2 (0.65) | CYP1A2CYP3A4CYP2C19TP53L3MBTL1 | |
| SCHEMBL4395749 | 0.78 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C19TP53L3MBTL1 | |
| SCHEMBL10099058 | 0.78 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C19TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976829-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2008-10-08 | — | — | EP | claimed |
| US-20070265262-A1 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. | 2007-11-15 | — | — | US | claimed |
| WO-2007070556-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2007-06-21 | — | — | WO | claimed |
| US-9796676-B2 | Honeybee repellents and uses thereof | INSCENT, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20160251312-A1 | Honeybee Repellents and Uses Thereof | INSCENT, INC. (US) | 2016-09-01 | — | — | US | disclosed |
| US-9357781-B2 | Honeybee repellents and uses thereof | INSCENT, INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-20140329674-A1 | Honeybee Repellents and Uses Thereof | INSCENT, INC. (US) | 2014-11-06 | — | — | US | disclosed |
| US-7629340-B2 | N-(6-membered aromatic ring)-amido anti-viral compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-08 | — | — | US | disclosed |
| EP-1976829-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2008-10-08 | — | — | EP | disclosed |
| US-20070265262-A1 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. | 2007-11-15 | — | — | US | disclosed |
| WO-2007070556-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2007-06-21 | — | — | WO | disclosed |
| WO-2007039609-A1 | PYRANODIBENZOFURAN DERIVATIVES WITH ANTIFUNGAL AND ANTIBACTERIAL ACTIVITY | INSTITUT PASTEUR (FR) | 2007-04-12 | — | — | WO | disclosed |
| US-5604280-A | PHOTOCHROMIC | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1997-02-18 | — | — | US | disclosed |
| EP-0676401-A1 | Annelated spirofluorene-2H-benzopyrans and their use in ophthalmic optics | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1995-10-11 | — | — | EP | disclosed |
| EP-0420571-A2 | 6-and/or 7-substituted -1,2,3,4,4A,9B-hexahydro-8-hydroxydibenzofuran-3-ols as inhibitors of leukotriene biosynthesis | MERCK & CO. INC. (US) | 1991-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160251312-A1 | Honeybee Repellents and Uses Thereof | ACHE, AHNAK, L3MBTL3 | CYP1A2 1536/4885CYP3A4 2778/4885CYP2C19 3907/4885 |
| US-20070265262-A1 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | ZC3HAV1, HAVCR2, ZC3HAV1L | CYP1A2 2802/4885CYP3A4 1952/4885CYP2C19 3413/4885 |
| US-20140329674-A1 | Honeybee Repellents and Uses Thereof | ACHE, AHNAK, L3MBTL3 | CYP1A2 1536/4885CYP3A4 2778/4885CYP2C19 3907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.