Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996803 | 0.90 | MAPT (0.58) | RAB9ANPC1GAAMAPTXBP1 | |
| SCHEMBL23484460 | 0.86 | MAPK1 (0.65) | RAB9ANPC1GAAMAPTXBP1 | |
| SCHEMBL18652192 | 0.83 | ADRB2 (0.57) | RAB9ANPC1ESR1ESR2ADRB2 | |
| SCHEMBL23484564 | 0.83 | ADRB2 (0.57) | RAB9ANPC1GAAMAPTXBP1 | |
| SCHEMBL14076762 | 0.82 | ELANE (0.59) | RAB9ANPC1GAAMAPTXBP1 | |
| SCHEMBL23484318 | 0.82 | MAPK1 (0.59) | RAB9ANPC1GAAMAPTXBP1 | |
| SCHEMBL17177747 | 0.81 | RAB9A (0.58) | RAB9ANPC1ESR1ESR2ADRB2 | |
| SCHEMBL23484462 | 0.81 | MAPK1 (0.62) | RAB9ANPC1SMN1; SMN2TDP1ESR1 | |
| SCHEMBL7773822 | 0.80 | RAB9A (0.61) | RAB9ANPC1TDP1ESR1ESR2 | |
| SCHEMBL1434120 | 0.80 | MAPK1 (0.71) | RAB9ANPC1GAAMAPTXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112274-B1 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2009-12-09 | — | — | EP | disclosed |
| EP-1112274-B1 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2009-12-09 | — | — | EP | disclosed |
| US-7422908-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-09-09 | — | — | US | disclosed |
| US-7422908-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-09-09 | — | — | US | disclosed |
| US-7422908-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-09-09 | — | — | US | disclosed |
| US-7416898-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-08-26 | — | — | US | disclosed |
| US-7416898-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-08-26 | — | — | US | disclosed |
| US-7416898-B2 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P | 2008-08-26 | — | — | US | disclosed |
| US-6767716-B2 | THE 1,2-DIOXETANE; A POLYMERIC ENHANCER WHICH IS EITHER AN AMMONIUM OR PHOSPHONIUM SALT OF A POLYVINYLBENZYL CHLORIDE AND AN AQUEOUS ENZYME DILUENT OR STABILIZER; DETECTION OF PHOSPHATASE, BETA-GALACTOSIDASE, AND CHOLINESTERASE | GIRI BRIJ P (US) | 2004-07-27 | — | — | US | disclosed |
| US-20040077018-A1 | Chemiluminescent 1,2-dioxetanes | GIRI BRIJ P (US) | 2004-04-22 | — | — | US | disclosed |
| US-6461876-B1 | STABLE SPIROFUSED RINGS; DECOMPOSING TO GENERATE LIGHT AND CARBONYL GROUP; HIGH ENERGY; MEDICINE | TOBEN, HOWARD R. | 2002-10-08 | — | — | US | disclosed |
| EP-1112274-A4 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-0790991-B1 | NOVEL 1,2-DIOXETANE COMPOUNDS WITH HALOALKOXY GROUPS, METHODS OF PREPARATION AND USE | TROPIX INC (US) | 2002-05-29 | — | — | EP | disclosed |
| US-20020013250-A1 | Single molecule detection of alkaline phosphatase enzyme using enhanced chemiluminescence from 1,2-dioxetanes and water-soluble, water-insoluble or partially-water soluble polymers | GIRI BRIJ P (US) | 2002-01-31 | — | — | US | disclosed |
| EP-1112274-A1 | CHEMILUMINESCENT 1,2-DIOXETANES | Giri, Brij P. (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000014092-A1 | CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2000-03-16 | — | — | WO | disclosed |
| US-5773628-A | CHEMILUMINESCENT ASSAY OF PHOSPHATASE | TROPIX, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0790991-A4 | — | — | 1997-09-03 | — | — | EP | disclosed |
| EP-0790991-A1 | NOVEL 1,2-DIOXETANE COMPOUNDS WITH HALOALKOXY GROUPS, METHODS OF PREPARATION AND USE | TROPIX, INC. (US) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996015122-A1 | NOVEL 1,2-DIOXETANE COMPOUNDS WITH HALOALKOXY GROUPS, METHODS OF PREPARATION AND USE | TROPIX, INC. (US) | 1996-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077018-A1 | Chemiluminescent 1,2-dioxetanes | CYP19A1, CYP1A1, CYP2F1 | RAB9A 2049/4885NPC1 4077/4885GAA 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.