SCHEMBL1996803

SCHEMBL1996803

O=C(OCC(F)(F)F)c1cccc(C(=O)OCC(F)(F)F)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.58
NPC1 O15118 2/20 0.58
XBP1 P17861 2/20 0.58
RAB9A P51151 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
GAA P10253 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
MAPK1 P28482 1/20 0.53
HIF1A Q16665 1/20 0.53
JMJD6 Q6NYC1 1/20 0.52
CES2 O00748 1/20 0.48
PRKCA P17252 1/20 0.48
PRKCD Q05655 1/20 0.48
ELANE P08246 4/20 0.47
LMNA P02545 2/20 0.47
F2 P00734 1/20 0.47
PLAU P00749 1/20 0.47
ALDH1A1 P00352 3/20 0.44
HPGD P15428 2/20 0.44
GABRA1 P14867 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4395859 0.90 RAB9A (0.60) MAPTNPC1XBP1RAB9ASMN1; SMN2
SCHEMBL14076762 0.88 ELANE (0.59) MAPTNPC1XBP1RAB9ASMN1; SMN2
SCHEMBL1434120 0.86 MAPK1 (0.71) MAPTNPC1XBP1RAB9ASMN1; SMN2
SCHEMBL1496824 0.84 MAPK1 (0.55) MAPTNPC1XBP1RAB9ASMN1; SMN2
SCHEMBL1998060 0.81 MAPK1 (0.46) MAPTNPC1XBP1RAB9ASMN1; SMN2
SCHEMBL9295363 0.81 MAPK1 (0.53) TDP1MAPK1HIF1ALMNAALDH1A1
SCHEMBL18724910 0.80 CES2 (0.57) NPC1XBP1RAB9ASMN1; SMN2CES2
SCHEMBL6139471 0.79 CYP4F2 (0.49) NPC1RAB9ATDP1MAPK1HIF1A
SCHEMBL19321932 0.79 HTR7 (0.48) MAPTNPC1XBP1RAB9ASMN1; SMN2
SCHEMBL27367228 0.78 TDP1 (0.45) NPC1RAB9ATDP1MAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed
US-20080146768-A1 PROCESSES FOR PREPARING POLYMERS USING ALPHA,OMEGA-DIFUNCTIONAL ALDARAMIDES E. I. DU PONT DE NEMOURS AND COMPANY 2008-06-19 US disclosed
EP-1858955-A1 PROCESSES USING ALPHA, OMEGA-DIFUNCTIONAL ALDARAMIDES AS MONOMERS AND CROSSLINKERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-11-28 EP disclosed
WO-2006091901-A1 PROCESSES USING ALPHA, OMEGA-DIFUNCTIONAL ALDARAMIDES AS MONOMERS AND CROSSLINKERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-08-31 WO disclosed