SCHEMBL4395869

SCHEMBL4395869

CCCCC=CC=COC

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.46
FASN P49327 1/20 0.41
FAAH O00519 4/20 0.34
TRPV1 Q8NER1 1/20 0.34
F7 P08709 1/20 0.34
F3 P13726 1/20 0.34
LPAR2 Q9HBW0 2/20 0.34
LPAR3 Q9UBY5 2/20 0.34
LPAR1 Q92633 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4395866 1.00 TSHR (0.46) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL4074574 0.84
SCHEMBL387383 0.84
SCHEMBL2274578 0.84 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL26905336 0.84 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL2274584 0.84 TSHR (0.59) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL1180790 0.82 TSHR (0.48) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL875892 0.82 TSHR (0.48) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL2273586 0.78 TSHR (0.54) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL2571772 0.78 TSHR (0.68) TSHRALDH1A1FASNFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11999674-B2 Butadiene telomerization catalyst preparation and use thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2024-06-04 US claimed
US-20230331643-A1 BUTADIENE TELOMERIZATION CATALYST PREPARATION AND USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-19 US claimed
US-11713286-B2 Butadiene telomerization catalyst preparation and use thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2023-08-01 US claimed
US-20220213006-A1 BUTADIENE TELOMERIZATION CATALYST PREPARATION AND USE THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2022-07-07 US claimed
US-11312670-B2 Butadiene telomerization catalyst and preparation thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2022-04-26 US claimed
CN-107438630-B Butadiene short-chain polymerization catalyst and preparation thereof 陶氏环球技术有限责任公司 2020-09-15 CN claimed
EP-3280690-B1 BUTADIENE TELOMERIZATION CATALYST AND PREPARATION THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-19 EP claimed
US-20180072637-A1 BUTADIENE TELOMERIZATION CATALYST AND PREPARATION THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2018-03-15 US claimed
EP-3280690-A1 BUTADIENE TELOMERIZATION CATALYST AND PREPARATION THEREOF Dow Global Technologies LLC (US) 2018-02-14 EP claimed
EP-3080136-A2 BUTADIENE TELOMERIZATION CATALYST PRECURSOR PREPARATION Dow Global Technologies Llc (US) 2016-10-19 EP claimed
WO-2016164258-A1 BUTADIENE TELOMERIZATION CATALYST AND PREPARATION THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2016-10-13 WO claimed
US-20160271601-A1 BUTADIENE TELOMERIZATION CATALYST PRECURSOR PREPARATION DOW OLEFINVERBUND GMBH (DE) 2016-09-22 US claimed
WO-2015088867-A2 BUTADIENE TELOMERIZATION CATALYST PRECURSOR PREPARATION DOW GLOBAL TECHNOLOGIES LLC (US) 2015-06-18 WO claimed
US-5004568-A Reacting With Carbon Monoxide Using A Group 8 Noble Metal Halide Catalyst And A Group 1B Metal Halide NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1991-04-02 US claimed
US-4767574-A CATALYTIC WITH GROUP 8 NOBLE METAL HALIDE AND HALIDE COMPOUND NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1988-08-30 US claimed
US-4642392-A Conjugated alkadiene telomerization to organo-oxyalkadienes NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1987-02-10 US claimed
US-4622416-A GROUP 8 HALIDE CATALYSTS NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1986-11-11 US claimed
US-4078005-A BROMINATION CHEMISCHE WERKE HUELS AKTIENGESELLSCHAFT (DT) 1978-03-07 US claimed
US-11999674-B2 Butadiene telomerization catalyst preparation and use thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2024-06-04 US disclosed
US-4078005-A BROMINATION CHEMISCHE WERKE HUELS AKTIENGESELLSCHAFT (DT) 1978-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11312670-B2 Butadiene telomerization catalyst and preparation thereof TELO2, TERT, POT1 TSHR 1679/4885ALDH1A1 824/4885FASN 4041/4885
US-11713286-B2 Butadiene telomerization catalyst preparation and use thereof TELO2, TERT, TPR TSHR 1701/4885ALDH1A1 954/4885FASN 3788/4885
US-20180072637-A1 BUTADIENE TELOMERIZATION CATALYST AND PREPARATION THEREOF TELO2, TERT, POT1 TSHR 1679/4885ALDH1A1 824/4885FASN 4041/4885
US-20230331643-A1 BUTADIENE TELOMERIZATION CATALYST PREPARATION AND USE THEREOF TELO2, TERT, TPR TSHR 1701/4885ALDH1A1 954/4885FASN 3788/4885
US-20220213006-A1 BUTADIENE TELOMERIZATION CATALYST PREPARATION AND USE THEREOF TELO2, TERT, TPR TSHR 1701/4885ALDH1A1 954/4885FASN 3788/4885
US-11999674-B2 Butadiene telomerization catalyst preparation and use thereof TELO2, TERT, TPR TSHR 1701/4885ALDH1A1 954/4885FASN 3788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.