Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743847 | 0.81 | ACE (0.55) | TSHR | |
| SCHEMBL4528488 | 0.81 | L3MBTL1 (0.49) | HPGDTSHRCHRM1GAA | |
| SCHEMBL4391732 | 0.77 | ALDH1A1 (0.51) | HPGDTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL4031425 | 0.76 | PPARA (0.57) | — | |
| SCHEMBL1462830 | 0.76 | CYP1A2 (0.44) | CHRM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6162439 | 0.76 | HDAC8 (0.58) | HPGDTSHRMAPK1ALDH1A1KMT2A | |
| SCHEMBL4380565 | 0.75 | CHRM1 (0.51) | CHRM1ALDH1A1 | |
| SCHEMBL8883817 | 0.74 | CHRM1 (0.43) | CHRM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4383425 | 0.74 | CHRM1 (0.50) | CHRM1ALDH1A1 | |
| SCHEMBL1461890 | 0.73 | EPHX1 (0.41) | CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005309-A1 | SUBSTITUTED PIPERIDINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| WO-2008144602-A1 | DEUTERATED ZAMIFENACIN DERIVATIVES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005309-A1 | SUBSTITUTED PIPERIDINES | CHRM3, CHRM2, CHRM5 | HPGD 877/4885TSHR 299/4885MAPK1 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.