Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398323 | 0.81 | KDM4E (0.38) | ALDH1A1KDM4EKMT2AMEN1CYP2D6 | |
| SCHEMBL5656404 | 0.79 | NPC1 (0.43) | KMT2AMEN1TSHRNPC1LTA4H | |
| SCHEMBL4395886 | 0.77 | HPGD (0.47) | ALDH1A1KMT2AMEN1TSHRHPGD | |
| SCHEMBL3784355 | 0.76 | SIGMAR1 (0.44) | ALDH1A1KMT2AMEN1TSHRLTA4H | |
| SCHEMBL5774496 | 0.76 | TSHR (0.41) | ALDH1A1KMT2ATSHRPOLBHPGD | |
| SCHEMBL4889326 | 0.76 | MEN1 (0.43) | ALDH1A1KMT2AMEN1TSHRCYP2D6 | |
| SCHEMBL8499574 | 0.74 | PRMT5 (0.48) | POLBHTT | |
| SCHEMBL1299631 | 0.74 | SIGMAR1 (0.52) | ALDH1A1KDM4EKMT2ATSHRPOLB | |
| SCHEMBL5750199 | 0.73 | GRIN2D (0.40) | ALDH1A1TSHRHTTOPRK1CYP2D6 | |
| Hydrochloric Acid SCHEMBL1299136 | 0.73 | SIGMAR1 (0.51) | ALDH1A1KDM4EKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005309-A1 | SUBSTITUTED PIPERIDINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| WO-2008144602-A1 | DEUTERATED ZAMIFENACIN DERIVATIVES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005309-A1 | SUBSTITUTED PIPERIDINES | CHRM3, CHRM2, CHRM5 | ALDH1A1 397/4885KDM4E 2817/4885KMT2A 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.