Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656969 | 0.85 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MAPKAPK2ALDH1A1 | |
| SCHEMBL85663 | 0.85 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MAPKAPK2WEE1 | |
| SCHEMBL655077 | 0.84 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3MAPKAPK2WEE1 | |
| SCHEMBL3667484 | 0.84 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3MAPKAPK2WEE1 | |
| SCHEMBL1584076 | 0.84 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3MAPKAPK2WEE1 | |
| SCHEMBL8286227 | 0.84 | ADRB1 (0.52) | SLC6A2SLC6A4SLC6A3MAPKAPK2MAP4K1 | |
| Hydrochloric Acid SCHEMBL1583516 | 0.84 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3MAPKAPK2ALDH1A1 | |
| SCHEMBL532873 | 0.83 | NPC1 (0.50) | SLC6A2SLC6A4SLC6A3MAPKAPK2 | |
| Hydrochloric Acid SCHEMBL1583739 | 0.82 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MAPKAPK2WEE1 | |
| Hydrochloric Acid SCHEMBL3657338 | 0.82 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3MAPKAPK2WEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058132-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | disclosed |