Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1583739 | 0.98 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MAPKAPK2KMT2A | |
| SCHEMBL85663 | 0.84 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MAPKAPK2KMT2A | |
| SCHEMBL4396319 | 0.84 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MAPKAPK2ALDH1A1 | |
| SCHEMBL3656969 | 0.84 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MAPKAPK2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1583516 | 0.82 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3MAPKAPK2ALDH1A1 | |
| SCHEMBL3667484 | 0.82 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3MAPKAPK2MGLL | |
| SCHEMBL8286227 | 0.82 | ADRB1 (0.52) | SLC6A2SLC6A4SLC6A3MAPKAPK2KMT2A | |
| SCHEMBL655077 | 0.82 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3MAPKAPK2KMT2A | |
| SCHEMBL532873 | 0.81 | NPC1 (0.50) | SLC6A2SLC6A4SLC6A3MAPKAPK2KMT2A | |
| SCHEMBL21595106 | 0.81 | MAPKAPK2 (0.47) | SLC6A2SLC6A4SLC6A3MAPKAPK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |
| US-20040214832-A1 | Piperazine derivative renin inhibitors | WARNER-LAMBERT COMPANY LLC | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214832-A1 | Piperazine derivative renin inhibitors | REN, ACE, AGTR2 | SLC6A2 1310/4885SLC6A4 1940/4885SLC6A3 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.