Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4405568 | 0.92 | ALDH1A1 (0.37) | SOS1MAOBMAOABDKRB1TDP1 | |
| Hydrochloric Acid SCHEMBL4397030 | 0.92 | DRD2 (0.35) | MAOBMAOATDP1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL4406718 | 0.90 | ALDH1A1 (0.32) | MAOBTDP1ALDH1A1TSHRHTT | |
| Hydrochloric Acid SCHEMBL4396994 | 0.90 | SMN1; SMN2 (0.31) | TDP1ALDH1A1TSHRHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4400750 | 0.90 | SMN1; SMN2 (0.32) | BDKRB1TDP1ALDH1A1TSHRHTT | |
| SCHEMBL915514 | 0.90 | MLLT1 (0.37) | SOS1MAOBMAOABDKRB1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4406711 | 0.89 | TDP1 (0.32) | TDP1ALDH1A1TSHRHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4409030 | 0.89 | ALDH1A1 (0.37) | SOS1MAOBMAOABDKRB1TDP1 | |
| SCHEMBL4411259 | 0.88 | MAOB (0.40) | MAOBALDH1A1SMN1; SMN2MCHR1SIGMAR1 | |
| SCHEMBL4404574 | 0.88 | ALDH1A1 (0.34) | MAOBTDP1ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |