Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4410339 | 0.91 | MAOB (0.34) | MAOBALDH1A1MCHR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4409030 | 0.91 | ALDH1A1 (0.37) | MAOBALDH1A1LTA4HSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4397030 | 0.90 | DRD2 (0.35) | MAOBALDH1A1 | |
| Hydrochloric Acid SCHEMBL4406718 | 0.90 | ALDH1A1 (0.32) | MAOBALDH1A1LMNA | |
| SCHEMBL13593470 | 0.90 | MAOB (0.43) | MAOBALDH1A1MCHR1LTA4HKMT2A | |
| SCHEMBL4404574 | 0.90 | ALDH1A1 (0.34) | MAOBALDH1A1MCHR1KMT2A | |
| SCHEMBL913973 | 0.90 | MAOB (0.43) | MAOBALDH1A1MCHR1LTA4HKMT2A | |
| Hydrochloric Acid SCHEMBL4406706 | 0.89 | ALDH1A1 (0.34) | ALDH1A1MCHR1KMT2A | |
| SCHEMBL4403829 | 0.88 | MAOB (0.44) | MAOBALDH1A1MCHR1LTA4HMEN1 | |
| SCHEMBL4396348 | 0.88 | SOS1 (0.34) | MAOBALDH1A1MCHR1SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |