Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylsulfane SCHEMBL4401424 | 0.88 | KMT2A (0.37) | KMT2ACA1CA2CA7CA9 | |
| (Phenylsulfinyl)Benzene SCHEMBL4396355 | 0.87 | KMT2A (0.32) | KMT2ACA1PPARACA2CA7 | |
| SCHEMBL1578765 | 0.82 | KMT2A (0.41) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL3468136 | 0.82 | KMT2A (0.41) | KMT2ACA1CA2CA7CA9 | |
| Diphenylsulfane SCHEMBL4398858 | 0.79 | CA1 (0.40) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL23292518 | 0.77 | CA1 (0.44) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL1479599 | 0.77 | CA1 (0.44) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL1674203 | 0.77 | CA1 (0.44) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL2290678 | 0.77 | CA1 (0.44) | KMT2ACA1CA2CA7CA9 | |
| Diphenylsulfane SCHEMBL4401428 | 0.77 | KMT2A (0.35) | KMT2ACA1PPARACA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473671-B2 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2009-01-06 | — | — | US | disclosed |
| US-7331920-B2 | Glycopeptide antibiotics, combinational libraries of glycopeptide antibiotics and methods of producing same | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2008-02-19 | — | — | US | disclosed |
| US-20050075483-A1 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | TRUSTEES OF PRINCETON UNIVERSITY | 2005-04-07 | — | — | US | disclosed |
| US-20040106772-A1 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | TRUSTEES OF PRINCETON UNIVERSITY, THE | 2004-06-03 | — | — | US | disclosed |
| US-6710168-B1 | VANCOMYCIN DERIVATIVES | THE TRUSTEES OF THE UNIVERSITY OF PRINCETON | 2004-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106772-A1 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | NPR1, NPR3, OSTC | KMT2A 4039/4885CA1 3479/4885PPARA 4083/4885 |
| US-20050075483-A1 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | ARSA, STS, GARS1 | KMT2A 3654/4885CA1 2567/4885PPARA 1724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.