Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 17/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 17/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 13/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396503 | 1.00 | ADRB1 (0.45) | ADRB1ADRB3ADRB2 | |
| SCHEMBL1622718 | 0.85 | BACE1 (0.43) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6805619 | 0.83 | ADRB3 (0.45) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6805613 | 0.83 | ADRB3 (0.45) | ADRB1ADRB3ADRB2 | |
| SCHEMBL4585166 | 0.80 | MEN1 (0.50) | ADRB1ADRB3ADRB2 | |
| SCHEMBL4585162 | 0.80 | MEN1 (0.50) | ADRB1ADRB3ADRB2 | |
| SCHEMBL1622719 | 0.80 | ADRB3 (0.41) | ADRB1ADRB3ADRB2 | |
| SCHEMBL4469616 | 0.76 | ADRB3 (0.49) | ADRB1ADRB3ADRB2 | |
| SCHEMBL5669438 | 0.76 | ADRB3 (0.49) | ADRB1ADRB3ADRB2 | |
| SCHEMBL4465920 | 0.73 | GLI1 (0.47) | ADRB1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791811-B1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2009-12-23 | — | — | EP | disclosed |
| US-7417060-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20080039506-A1 | Aminoalcohol Derivatives | ASTELLAS PHARMA INC. (JP) | 2008-02-14 | — | — | US | disclosed |
| US-20050137236-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137236-A1 | Aminoalcohol derivatives | GPR39, PRMT9, CHRM2 | ADRB1 70/4885ADRB3 86/4885ADRB2 58/4885 |
| US-20080039506-A1 | Aminoalcohol Derivatives | HRH4, HRH2, CBR3 | ADRB1 19/4885ADRB3 40/4885ADRB2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.