Biphenyl

Biphenyl

SCHEMBL4396858

C[PH+](C)C.c1ccc(-c2ccccc2)cc1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
SLC22A2 O15244 1/20 0.40
SLC22A1 O15245 1/20 0.40
SLC22A3 O75751 1/20 0.40
SLC6A4 P31645 1/20 0.40
TAAR1 Q96RJ0 3/20 0.38
CYP1A2 P05177 2/20 0.38
HSD17B10 Q99714 2/20 0.38
MAPK1 P28482 1/20 0.38
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NOTUM Q6P988 1/20 0.38
MMP3 P08254 1/20 0.38
BCL2L1 Q07817 1/20 0.38
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
ATM Q13315 1/20 0.35
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5089460 0.94 ALDH1A1 (0.39) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL3652128 0.85 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL19977300 0.82 ALDH1A1 (0.56) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL19977293 0.82 ALDH1A1 (0.56) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL24518410 0.82 ALDH1A1 (0.56) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL24518243 0.82 ALDH1A1 (0.56) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL19977298 0.82 ALDH1A1 (0.56) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL11707018 0.82 ALDH1A1 (0.50) ALDH1A1TAAR1CYP1A2HSD17B10MAPK1
Benzene SCHEMBL31091106 0.82 ALDH1A1 (0.50) ALDH1A1TAAR1CYP1A2HSD17B10MAPK1
SCHEMBL143876 0.82 ALDH1A1 (0.50) ALDH1A1TAAR1CYP1A2HSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629431-B2 Polycarbonate prepolymer for solid phase polymerization and process for producing polycarbonate IDEMITSU KOSAN CO., LTD. (JP) 2009-12-08 US disclosed
US-7390868-B2 Catalyst for polycarbonate production and process for producing polycarbonate NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-06-24 US disclosed
US-20080064847-A1 Oxidative carbonylation; molecular weight control IDEMISU KOSAN CO., LTD. (JP) 2008-03-13 US disclosed
US-20070043199-A1 Catalyst for polycarbonate production and process for producing polycarbonate IDEMITSU KOSAN CO., LTD. (JP) 2007-02-22 US disclosed
US-5922826-A TRANSESTERIFICATION IN PRESENCE OF A POLYMERIZATION CATALYST CONTAINING AN ORGANONITROGEN COMPOUND AND A QUATERNARY PHOSPHONIUM SALT TO PRODUCE POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 1999-07-13 US disclosed
EP-0807657-A1 PROCESS FOR PRODUCING POLYCARBONATE IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-11-19 EP disclosed