Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957033 | 0.83 | MMP13 (0.48) | LCKSCN9AHSD17B10MMP13KDM4E | |
| SCHEMBL4072714 | 0.81 | GSK3B (0.42) | LCKSCN9AMMP13GSK3BDYRK1A | |
| SCHEMBL21964493 | 0.81 | LCK (0.43) | LCKSCN9ABCHEGSK3BDYRK1A | |
| SCHEMBL29510855 | 0.81 | LCK (0.43) | LCKSCN9ABCHEGSK3BDYRK1A | |
| SCHEMBL21964304 | 0.79 | BCHE (0.42) | LCKSCN9ABCHEGSK3BDYRK1A | |
| SCHEMBL4391943 | 0.76 | ALDH1A1 (0.43) | KDM4EPOLB | |
| SCHEMBL4067752 | 0.75 | HSD17B10 (0.39) | HSD17B10MMP13MAPK1KDM4EPOLB | |
| SCHEMBL21874314 | 0.74 | SCN9A (0.37) | LCKSCN9ABCHEGSK3BDYRK1A | |
| SCHEMBL13350140 | 0.72 | LCK (0.55) | LCKBCHEHSD17B10MMP13MAPK1 | |
| SCHEMBL30317103 | 0.72 | NPC1 (0.44) | LCKSCN9ABCHEMMP13KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |