Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961035 | 0.80 | KDM4E (0.58) | HSD17B10ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL3943265 | 0.78 | CYP2A6 (0.49) | HSD17B10ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL4039329 | 0.77 | ATAD2 (0.49) | HSD17B10ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL4070943 | 0.76 | GABRA1 (0.36) | HSD17B10ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL4397179 | 0.75 | LCK (0.38) | HSD17B10KDM4EMMP13ADORA3POLB | |
| SCHEMBL18886844 | 0.73 | GAA (0.48) | HSD17B10CA2ALDH1A1KDM4ERAB9A | |
| SCHEMBL5260106 | 0.73 | KDM4E (0.48) | HSD17B10ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL4707817 | 0.72 | KDM4E (0.48) | HSD17B10ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL18886853 | 0.72 | KMT2A (0.54) | HSD17B10ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL18886841 | 0.72 | GABRA1 (0.46) | HSD17B10ALDH1A1KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |