SCHEMBL4397208

SCHEMBL4397208

C1=CON(c2ccccc2)O1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
KDM4E B2RXH2 3/20 0.35
HPGD P15428 2/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MGLL Q99685 1/20 0.35
POLB P06746 1/20 0.34
GSK3A P49840 3/20 0.33
GSK3B P49841 3/20 0.33
GAA P10253 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
ADRB1 P08588 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3412417 0.69 LMNA (0.41) LMNAKDM4EHPGDATML3MBTL1
SCHEMBL10582068 0.69 LMNA (0.46) LMNAKDM4EHPGDATML3MBTL1
SCHEMBL7845754 0.69 GSK3A (0.37) LMNAKDM4EHPGDATML3MBTL1
SCHEMBL3330316 0.67 GSK3A (0.37) LMNAKDM4EATML3MBTL1GSK3A
Hydrochloric Acid SCHEMBL5446411 0.67 LMNA (0.39) LMNAKDM4EHPGDATML3MBTL1
SCHEMBL7113548 0.65 POLB (0.35) LMNAKDM4EHPGDATML3MBTL1
SCHEMBL6049417 0.65 LMNA (0.43) LMNAKDM4EL3MBTL1GAASIGMAR1
SCHEMBL2466051 0.65 LMNA (0.42) LMNAKDM4EHPGDATML3MBTL1
SCHEMBL24776903 0.63 MGLL (0.44) LMNAATMMGLLGSK3AGSK3B
SCHEMBL251532 0.62 LMNA (0.35) LMNASIGMAR1MEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1788044-B1 Ink-jet ink, ink-jet ink set, and ink-jet recording method KONICA MINOLTA HOLDINGS INC (JP) 2009-12-23 EP disclosed
EP-1788044-A1 Ink-jet ink, ink-jet ink set, and ink-jet recording method KONICA MINOLTA HOLDINGS, INC. (JP) 2007-05-23 EP disclosed
US-20070109375-A1 INK-JET INK, INK-JET INK SET AND INK-JET RECORDING METHOD KONICA MINOLTA HOLDINGS, INC. (JP) 2007-05-17 US disclosed