Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397208 | 0.69 | LMNA (0.37) | GSK3AGSK3BLMNAALDH1A1HPGD | |
| SCHEMBL3412417 | 0.67 | LMNA (0.41) | LMNAALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL10582068 | 0.67 | LMNA (0.46) | LMNAALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL13078390 | 0.65 | GAA (0.46) | ALDH1A1TSHRKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5446411 | 0.65 | LMNA (0.39) | LMNAALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL25902071 | 0.63 | ALDH1A1 (0.40) | GSK3AGSK3BLMNAALDH1A1KDM4E | |
| SCHEMBL6049417 | 0.63 | LMNA (0.43) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2466051 | 0.63 | LMNA (0.42) | GSK3AGSK3BLMNAALDH1A1HPGD | |
| SCHEMBL2390706 | 0.61 | KDM4E (0.50) | GSK3AGSK3BLMNAALDH1A1HPGD | |
| SCHEMBL13321978 | 0.59 | LMNA (0.39) | GSK3AGSK3BLMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686613-B1 | OZONIDE REDUCING AGENT | OTSUKA KAGAKU KK (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-5770729-A | SULFIDE COMPOUND WITH POLAR SUBSTITUENTS, FORMATION OF SULFOXIDE, MILD CONDITIONS, SAFE, NONPOLLUTING | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0686613-A1 | OZONIDE REDUCING AGENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |