Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919296 | 0.91 | RAB9A (0.76) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL10458108 | 0.87 | CYP1A2 (1.00) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL17266522 | 0.83 | CYP1A2 (0.90) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL8618993 | 0.82 | CYP1A2 (0.77) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL8914866 | 0.81 | CYP1A2 (0.88) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL9084215 | 0.81 | CYP1A2 (0.88) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL13698952 | 0.79 | CYP1A2 (0.68) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL5708657 | 0.79 | CYP1A2 (0.68) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL14846522 | 0.78 | CYP1A2 (0.67) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL18263348 | 0.78 | CYP1A2 (0.67) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572908-B2 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-7572908-B2 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-7572908-B2 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| WO-2007112264-A2 | CLEAVABLE LINKERS FOR POLYNUCLEOTIDES | AGILENT TECHNOLOGIES, INC. (US) | 2007-10-04 | — | — | WO | disclosed |
| US-20070224603-A1 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. | 2007-09-27 | — | — | US | disclosed |
| US-20070224603-A1 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. | 2007-09-27 | — | — | US | disclosed |
| US-20070224603-A1 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224603-A1 | Cleavable linkers for polynucleotides | PNKP, PCNA, TYMP | CYP1A2 4806/4885CYP2C19 4766/4885CYP2D6 4134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.