Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.76 |
| ▸ | NPC1 | O15118 | 3/20 | 0.76 |
| ▸ | CASP3 | P42574 | 1/20 | 0.76 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.76 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.76 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397266 | 0.91 | CYP1A2 (0.77) | RAB9ASMN1; SMN2NPC1CASP3SENP8 | |
| SCHEMBL10421957 | 0.86 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1CASP3SENP8 | |
| SCHEMBL8618065 | 0.81 | NPC1 (0.76) | RAB9ASMN1; SMN2NPC1CASP3SENP8 | |
| SCHEMBL10508468 | 0.81 | RAB9A (0.76) | RAB9ASMN1; SMN2NPC1CASP3SENP8 | |
| SCHEMBL16444039 | 0.80 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1CASP3SENP8 | |
| SCHEMBL9113979 | 0.80 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1CASP3SENP8 | |
| SCHEMBL18377185 | 0.79 | NPC1 (0.63) | RAB9ASMN1; SMN2NPC1CASP3SENP8 | |
| SCHEMBL1471437 | 0.77 | NPC1 (0.61) | RAB9ASMN1; SMN2NPC1CASP3SENP8 | |
| SCHEMBL9856191 | 0.77 | NPC1 (0.64) | RAB9ASMN1; SMN2NPC1CASP3SENP8 | |
| SCHEMBL10458108 | 0.77 | CYP1A2 (1.00) | RAB9ASMN1; SMN2NPC1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811375-B1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| EP-0811375-A1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0469901-B1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5189211-A | Thromboxane A2 antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0469901-A1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-5075335-A | Enzyme inhibitors | EISAI CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-4948808-A | ENZYME INHIBITORS | EISAI CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0229370-B1 | GUANIDINOBENZOIC ESTER DERIVATIVE, A PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Eisai Co., Ltd. (JP) | 1989-04-19 | — | — | EP | disclosed |
| US-4801603-A | ENZYME INHIBITORS, TREATMENT OF PANCREATITIS, HEMORRHAGE, THROMBOSIS | EISAI CO., LTD. (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0229370-A1 | Guanidinobenzoic ester derivative, a process for preparing same and pharmaceutical compositions containing same | Eisai Co., Ltd. (JP) | 1987-07-22 | — | — | EP | disclosed |