SCHEMBL4397335

SCHEMBL4397335

CCOC(=O)c1ccccc1OC(=O)Oc1ccc(C)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
ALDH1A1 P00352 2/20 0.49
HSD17B10 Q99714 1/20 0.49
NPSR1 Q6W5P4 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
LMNA P02545 3/20 0.47
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
PTK2B Q14289 2/20 0.46
RXFP1 Q9HBX9 1/20 0.46
PTGS2 P35354 1/20 0.45
MAPT P10636 4/20 0.45
HPGD P15428 1/20 0.45
XBP1 P17861 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
ELANE P08246 1/20 0.44
PRTN3 P24158 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1282822 0.91 TSHR (0.59) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL5706220 0.90 TSHR (0.54) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL5706120 0.90 TSHR (0.54) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL5705989 0.90 TSHR (0.54) TSHRALDH1A1HSD17B10NPSR1MEN1
SCHEMBL5706235 0.90 TSHR (0.54) TSHRALDH1A1HSD17B10LMNAPTGS2
SCHEMBL1283310 0.89 TSHR (0.69) TSHRALDH1A1HSD17B10NPSR1MEN1
SCHEMBL4393205 0.89 PTK2B (0.52) TSHRALDH1A1HSD17B10NPSR1MEN1
SCHEMBL4394452 0.88 PTK2B (0.57) TSHRALDH1A1HSD17B10NPSR1MEN1
SCHEMBL6812182 0.87 TSHR (0.50) TSHRALDH1A1HSD17B10NPSR1MEN1
SCHEMBL5705984 0.87 TSHR (0.52) TSHRALDH1A1HSD17B10LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
EP-1412411-B1 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GEN ELECTRIC (US) 2006-08-09 EP disclosed
EP-1412411-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-04-28 EP disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
EP-1016648-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES ASAHI CHEMICAL IND (JP) 2003-05-14 EP disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
WO-2003008481-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-01-30 WO disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
US-6262210-B1 TRANSESTERIFYING DIALKYL CARBONATE, ALKYL ARYL CARBONATE OR MIXTURE WITH AROMATIC MONOHYDROXY COMPOUND IN PRESENCE OF METAL CONTAINING CATALYST TO OBTAIN HIGH BOILING POINT REACTION MIXTURE CONTAINING AROMATIC CARBONATE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-07-17 US disclosed
EP-1016648-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-07-05 EP disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 TSHR 4099/4885ALDH1A1 1791/4885HSD17B10 963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.