SCHEMBL4393205

SCHEMBL4393205

CCOC(=O)Oc1ccccc1C(=O)Oc1ccc(C)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2B Q14289 1/20 0.52
RXFP1 Q9HBX9 1/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
CYP3A4 P08684 1/20 0.52
NPSR1 Q6W5P4 3/20 0.51
MAPT P10636 3/20 0.51
HPGD P15428 1/20 0.51
XBP1 P17861 1/20 0.51
PTGS2 P35354 1/20 0.51
KMT2A Q03164 4/20 0.51
MEN1 O00255 2/20 0.51
TSHR P16473 2/20 0.47
ESR1 P03372 2/20 0.47
ESR2 Q92731 1/20 0.47
LMNA P02545 3/20 0.46
TP53 P04637 2/20 0.46
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4385296 0.91 HSD17B10 (0.54) CYP1A2CYP2C9CYP2C19NPSR1MAPT
SCHEMBL4397335 0.89 TSHR (0.56) PTK2BRXFP1CYP1A2CYP2C9CYP2C19
SCHEMBL4394452 0.88 PTK2B (0.57) PTK2BRXFP1CYP1A2CYP2C9CYP2C19
SCHEMBL4390471 0.85 PTK2B (0.55) PTK2BRXFP1CYP1A2CYP2C9CYP2C19
SCHEMBL4392103 0.85 ESR1 (0.62) PTK2BRXFP1CYP1A2CYP2C9CYP2C19
SCHEMBL13971012 0.85 PTK2B (0.55) PTK2BRXFP1CYP1A2CYP2C9CYP2C19
SCHEMBL4385356 0.85 HPGD (0.61) PTK2BRXFP1CYP1A2CYP2C9CYP2C19
SCHEMBL4391361 0.85 TSHR (0.67) PTK2BCYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL1914150 0.83 TSHR (0.55) PTK2BCYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL4393206 0.82 TSHR (0.50) CYP1A2CYP2C9CYP2C19NPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
EP-1016648-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES ASAHI CHEMICAL IND (JP) 2003-05-14 EP disclosed
US-6262210-B1 TRANSESTERIFYING DIALKYL CARBONATE, ALKYL ARYL CARBONATE OR MIXTURE WITH AROMATIC MONOHYDROXY COMPOUND IN PRESENCE OF METAL CONTAINING CATALYST TO OBTAIN HIGH BOILING POINT REACTION MIXTURE CONTAINING AROMATIC CARBONATE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-07-17 US disclosed
EP-1016648-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 PTK2B 1591/4885RXFP1 4648/4885CYP1A2 342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.