SCHEMBL4397435

SCHEMBL4397435

CCC(O)c1cccc(O)c1-c1ccccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
LMNA P02545 2/20 0.42
GCGR P47871 2/20 0.40
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRB3 P13945 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
ANPEP P15144 2/20 0.39
DPP4 P27487 2/20 0.39
MAPT P10636 5/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
MAOA P21397 3/20 0.38
HPGD P15428 5/20 0.37
ALDH1A1 P00352 4/20 0.37
HSD17B10 Q99714 4/20 0.37
ALOX15 P16050 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10532730 0.93 TSHR (0.48) TSHRLMNAGCGRGABRA1GABRB2
SCHEMBL7109459 0.86 HPGD (0.41) TSHRLMNAGCGRGABRA1GABRB2
SCHEMBL12610425 0.81 TSHR (0.65) TSHRLMNAGABRA1GABRB2ADRB1
SCHEMBL2990957 0.81 TSHR (0.65) TSHRLMNAGABRA1GABRB2ADRB1
SCHEMBL30295406 0.81 TSHR (0.65) TSHRLMNAGABRA1GABRB2ADRB1
SCHEMBL31519851 0.79 GABRA1 (0.59) TSHRLMNAGCGRGABRA1GABRB2
SCHEMBL9637441 0.79 GABRA1 (0.59) TSHRLMNAGCGRGABRA1GABRB2
SCHEMBL5907398 0.78 LMNA (0.54) TSHRLMNAGABRA1GABRB2ADRB1
Hydrochloric Acid SCHEMBL31519860 0.78 GABRA1 (0.57) TSHRLMNAGCGRGABRA1GABRB2
SCHEMBL2989016 0.77 TSHR (0.55) TSHRLMNAGABRA1GABRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
CN-101084181-B Preparation method of aromatic polycarbonate ASAHI CHEMICAL IND (JP) 2011-07-27 CN disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
CN-101084181-A Asahi chemical corp (jp) ASAHI CHEMICAL CORP (JP) 2007-12-05 CN disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
CN-1077097-C Process for producing aromatic carbonate ASAHI CHEMICAL IND (JP) 2002-01-02 CN disclosed
CN-1190952-A Process for producing aromatic carbonate ASAHI CHEMICAL IND (JP) 1998-08-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 TSHR 4099/4885LMNA 2641/4885GCGR 709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.