SCHEMBL2989016

SCHEMBL2989016

CCC(O)c1cccc(O)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
BCHE P06276 1/20 0.50
TYR P14679 1/20 0.50
ACHE P22303 1/20 0.50
LMNA P02545 4/20 0.44
HPGD P15428 3/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
ALDH1A1 P00352 2/20 0.44
ALOX15 P16050 2/20 0.44
HSD17B10 Q99714 2/20 0.44
ADAMTS4 O75173 1/20 0.44
EGFR P00533 1/20 0.44
FYN P06241 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
CA6 P23280 1/20 0.44
CDK2 P24941 1/20 0.44
MMP12 P39900 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2784586 0.83 TSHR (0.73) TSHRBCHETYRACHELMNA
SCHEMBL12610425 0.83 TSHR (0.65) TSHRBCHETYRACHELMNA
SCHEMBL2990957 0.83 TSHR (0.65) TSHRBCHETYRACHELMNA
SCHEMBL30295406 0.83 TSHR (0.65) TSHRBCHETYRACHELMNA
SCHEMBL11306339 0.81 LMNA (0.46) TSHRBCHETYRACHELMNA
SCHEMBL11043623 0.81 ADRA2A (0.55) TSHRLMNAHPGDCA1CA2
SCHEMBL2976451 0.81 ADRB2 (0.46) TSHRBCHETYRACHELMNA
SCHEMBL5589704 0.81 TSHR (0.52) TSHRBCHETYRACHELMNA
SCHEMBL4334723 0.81 ADRA2A (0.55) TSHRLMNAHPGDCA1CA2
SCHEMBL1068333 0.80 ADRA2A (0.67) TSHRBCHETYRACHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0446865-B1 Gelation of acrylamide-containing polymers with hydroxyphenyl alkanols PHILLIPS PETROLEUM CO (US) 1994-09-21 EP claimed
US-5100931-A Crosslinking; enhanced oil recovery PHILLIPS PETROLEUM COMPANY (US) 1992-03-31 US claimed
EP-0446865-A2 Gelation of acrylamide-containing polymers with hydroxyphenyl alkanols PHILLIPS PETROLEUM COMPANY (US) 1991-09-18 EP claimed
US-7777073-B2 Topical delivery system for antiaging and skin whitening agents BIODERM RESEARCH (US) 2010-08-17 US disclosed
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US disclosed
EP-0446865-B1 Gelation of acrylamide-containing polymers with hydroxyphenyl alkanols PHILLIPS PETROLEUM CO (US) 1994-09-21 EP disclosed
US-5100931-A Crosslinking; enhanced oil recovery PHILLIPS PETROLEUM COMPANY (US) 1992-03-31 US disclosed
EP-0446865-A2 Gelation of acrylamide-containing polymers with hydroxyphenyl alkanols PHILLIPS PETROLEUM COMPANY (US) 1991-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents TYR, MMP17, MMP1 TSHR 2624/4885BCHE 1800/4885TYR 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.