Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28878075 | 1.00 | HTR2C (0.52) | HTR2CGLAKMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL4389163 | 1.00 | HTR2C (0.52) | HTR2CGLAKMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL16707772 | 0.93 | PREP (0.50) | HTR2CGLASMN1; SMN2CYP2C19PARP1 | |
| SCHEMBL27530724 | 0.86 | GLA (0.51) | HTR2CGLAKMT2ASMN1; SMN2PARP1 | |
| SCHEMBL28899278 | 0.85 | KMT2A (0.55) | HTR2CGLAKMT2ASMN1; SMN2PARP1 | |
| SCHEMBL4387733 | 0.85 | KMT2A (0.55) | HTR2CGLAKMT2ASMN1; SMN2PARP1 | |
| SCHEMBL12189896 | 0.85 | KMT2A (0.55) | HTR2CGLAKMT2ASMN1; SMN2PARP1 | |
| SCHEMBL4389665 | 0.84 | KMT2A (0.49) | HTR2CGLAKMT2ASMN1; SMN2PARP1 | |
| SCHEMBL15289830 | 0.84 | KMT2A (0.49) | HTR2CGLAKMT2ASMN1; SMN2PARP1 | |
| SCHEMBL4392704 | 0.84 | PSEN1 (0.58) | HTR2CGLAKMT2ASMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240252655-A1 | DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS | NOVARTIS AG (CH) | 2024-08-01 | — | — | US | disclosed |
| EP-4329815-A1 | DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS | Novartis AG (CH) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022232634-A1 | DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS | NOVARTIS AG (CH) | 2022-11-03 | — | — | WO | disclosed |
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |
| EP-1051176-B1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARMA INC (US) | 2006-11-22 | — | — | EP | disclosed |
| US-20040102450-A1 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2004-05-27 | — | — | US | disclosed |
| EP-1051176-A4 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARM PROD INC (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| EP-1051176-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | Aventis Pharmaceuticals Products Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037304-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240252655-A1 | DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS | USP2, USP1, USP28 | HTR2C 4150/4885GLA 1225/4885KMT2A 2134/4885 |
| US-20040102450-A1 | Substituted oxoazaheterocyclyl compounds | F13B, F9, F11 | HTR2C 1330/4885GLA 174/4885KMT2A 2513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.