Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21375648 | 0.70 | SIGMAR1 (0.60) | OPRM1DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL4389325 | 0.70 | USP30 (0.37) | OPRM1USP30HRH1MAOAMAOB | |
| SCHEMBL28041067 | 0.68 | OPRM1 (0.62) | OPRM1DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL901151 | 0.67 | HTR2A (0.54) | OPRM1DRD3CHRM3HRH1CHRM1 | |
| SCHEMBL10563190 | 0.67 | OPRM1 (0.44) | OPRM1DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL4388093 | 0.67 | HRH3 (0.39) | SIGMAR1OPRD1 | |
| SCHEMBL1720308 | 0.66 | HTT (0.41) | DRD2DRD3HRH1OPRL1 | |
| SCHEMBL2896994 | 0.66 | L3MBTL3 (0.46) | OPRM1DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL4395992 | 0.65 | HRH3 (0.49) | SIGMAR1HTR7 | |
| SCHEMBL154565 | 0.65 | USP30 (0.37) | USP30HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838805-B1 | ORTHOGONALLY FIXED COMPOUNDS FOR ELECTROOPTICAL APPLICATIONS | UNIV BRAUNSCHWEIG TECH (DE) | 2009-12-02 | — | — | EP | claimed |