Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34467410 | 0.74 | HCAR3 (0.47) | MAPTSMN1; SMN2HCAR3ALDH1A1KMT2A | |
| SCHEMBL9725432 | 0.73 | SMN1; SMN2 (0.61) | MAPTSMN1; SMN2HCAR3ALDH1A1KMT2A | |
| SCHEMBL29994340 | 0.72 | HCAR3 (0.64) | HCAR3ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL9091485 | 0.72 | PARP1 (0.52) | MAPTSMN1; SMN2HCAR3ALDH1A1KMT2A | |
| SCHEMBL31042134 | 0.70 | ATM (0.43) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| Carbamic Acid SCHEMBL29141960 | 0.70 | ALDH1A1 (0.57) | MAPTSMN1; SMN2HCAR3ALDH1A1KMT2A | |
| SCHEMBL30503507 | 0.69 | HCAR3 (0.74) | MAPTSMN1; SMN2HCAR3ALDH1A1GAA | |
| SCHEMBL223645 | 0.69 | PARP1 (0.55) | MAPTSMN1; SMN2ALDH1A1GAAMAPK1 | |
| SCHEMBL29689258 | 0.69 | PARP1 (0.55) | MAPTSMN1; SMN2ALDH1A1GAAMAPK1 | |
| SCHEMBL29141958 | 0.69 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2HCAR3ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127815-A1 | AMINOALYL-IMIDAZOTETRAZINES FOR TREATMENT OF CANCER | THE UNIVERSITY OF BRADFORD (GB) | 2009-10-22 | — | — | WO | disclosed |