Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503507 | 0.80 | HCAR3 (0.74) | SMN1; SMN2MAPTHCAR3PARP1LMNA | |
| SCHEMBL9725444 | 0.76 | PIK3CD (0.47) | SMN1; SMN2MAPTHCAR3LMNAHTT | |
| SCHEMBL6013576 | 0.76 | ALDH1A1 (0.43) | HCAR3KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL4764057 | 0.74 | ALDH1A1 (0.45) | SMN1; SMN2MAPTHCAR3LMNAHTT | |
| SCHEMBL9725429 | 0.73 | PKM (0.65) | SMN1; SMN2MAPTHCAR3LMNAHTT | |
| SCHEMBL19436464 | 0.73 | PKM (0.65) | SMN1; SMN2MAPTHCAR3LMNAHTT | |
| SCHEMBL4397960 | 0.73 | MAPT (0.53) | SMN1; SMN2MAPTHCAR3PARP1LMNA | |
| SCHEMBL9725472 | 0.72 | TSHR (0.47) | MAPTHCAR3HTTKMT2AALDH1A1 | |
| SCHEMBL10665446 | 0.71 | HCAR3 (0.74) | SMN1; SMN2MAPTHCAR3PARP1LMNA | |
| SCHEMBL31217479 | 0.71 | MAPT (0.48) | SMN1; SMN2MAPTHCAR3PARP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |