Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CCL2 | P13500 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4473142 | 0.82 | HTR2A (0.40) | RETHTR2AKDM4EBRD4CCL2 | |
| SCHEMBL4384672 | 0.77 | RET (0.34) | RETHTR2AKDM4EBRD4CCL2 | |
| SCHEMBL6337587 | 0.67 | HTR2A (0.42) | RETHTR2AKDM4EBRD4CCL2 | |
| SCHEMBL7937440 | 0.64 | HTR2A (0.42) | RETHTR2AKDM4EBRD4CCL2 | |
| SCHEMBL4472241 | 0.64 | HTR2A (0.31) | RETHTR2AHRH1 | |
| SCHEMBL8147058 | 0.63 | HTR2A (0.38) | RETHTR2AKDM4EBRD4CCL2 | |
| SCHEMBL28249192 | 0.62 | HTR2A (0.41) | RETHTR2AKDM4EBRD4CCL2 | |
| Fluoride SCHEMBL3384859 | 0.62 | HTR2A (0.36) | RETHTR2AKDM4EBRD4CCL2 | |
| SCHEMBL797213 | 0.61 | HTR2A (0.36) | RETHTR2AKDM4EBRD4CCL2 | |
| SCHEMBL186866 | 0.60 | HTR2A (0.41) | RETHTR2AKDM4EBRD4CCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2017280-B1 | METALLOCENE COMPLEX AND POLYMERIZATION CATALYST COMPOSITION CONTAINING THE SAME | RIKEN (JP) | 2015-01-07 | — | — | EP | disclosed |
| US-8653290-B2 | Metallocene complex and polymerization catalyst composition containing the same | RIKEN (JP) | 2014-02-18 | — | — | US | disclosed |
| US-20090264604-A1 | Metallocene Complex and Polymerization Catalyst Composition Containing the Same | RIKEN (JP) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264604-A1 | Metallocene Complex and Polymerization Catalyst Composition Containing the Same | RTF1, POLR1A, POLR1G | RET 3554/4885HTR2A 4563/4885KDM4E 2126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.