Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28388622 | 0.85 | LMNA (0.31) | RET | |
| SCHEMBL4384672 | 0.70 | RET (0.34) | HTR2AHRH1RET | |
| SCHEMBL8861732 | 0.66 | HTR2A (0.51) | HTR2AHRH1RET | |
| SCHEMBL7946676 | 0.65 | HTR2A (0.32) | HTR2AHRH1 | |
| SCHEMBL28038419 | 0.64 | LMNA (0.34) | HTR2A | |
| SCHEMBL8375501 | 0.64 | LMNA (0.34) | HTR2A | |
| SCHEMBL12629758 | 0.64 | MAOA (0.37) | HTR2A | |
| SCHEMBL4398162 | 0.64 | RET (0.34) | HTR2AHRH1RET | |
| SCHEMBL8149969 | 0.63 | LMNA (0.35) | HTR2A | |
| SCHEMBL1453437 | 0.63 | HTR2A (0.42) | HTR2AHRH1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2017280-A1 | METALLOCENE COMPLEX AND POLYMERIZATION CATALYST COMPOSITION CONTAINING THE SAME | Riken (JP) | 2009-01-21 | — | — | EP | disclosed |