Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GGT1 | P19440 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010714 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL7613367 | 0.78 | KMT2A (0.49) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL6857330 | 0.78 | CTNNB1 (0.54) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL2953498 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL4398297 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL29080260 | 0.77 | KMT2A (0.49) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL7287255 | 0.77 | CA12 (0.66) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL2986261 | 0.77 | CA9 (0.59) | KDM4EALDH1A1LMNAHTTMAPK1 | |
| SCHEMBL8948126 | 0.76 | CA12 (0.52) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL11696928 | 0.75 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10HPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572907-B2 | Methods and compounds for polynucleotide synthesis | AGILENT TECHNOLOGIES, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| EP-1717242-A1 | Polynucleotide synthesis | Agilent Technologies, Inc. (US) | 2006-11-02 | — | — | EP | disclosed |
| US-20060247430-A1 | Methods and compounds for polynucleotide synthesis | AGILENT TECHNOLOGIES, INC. | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247430-A1 | Methods and compounds for polynucleotide synthesis | POLN, POLRMT, POLM | KDM4E 4662/4885ALDH1A1 3888/4885HSD17B10 2662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.