Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL4398709

NCc1cccc(C2CCN(C(=O)c3cccc(C#Cc4ccc(N)nc4)c3)CC2)c1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.55
TPSAB1 Q15661 16/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4406880 0.93 TPSAB1 (0.46) F10TPSAB1
Trifluoroacetic Acid SCHEMBL4409362 0.88 TPSAB1 (0.56) F10TPSAB1
Trifluoroacetic Acid SCHEMBL4411518 0.87 TPSAB1 (0.55) F10TPSAB1
Trifluoroacetic Acid SCHEMBL4406887 0.87 TPSAB1 (0.57) F10TPSAB1
Trifluoroacetic Acid SCHEMBL1382730 0.86 F10 (0.55) F10TPSAB1
Trifluoroacetic Acid SCHEMBL1382400 0.84 TPSAB1 (0.58) F10TPSAB1
Trifluoroacetic Acid SCHEMBL4407733 0.83 TPSAB1 (0.55) F10TPSAB1
Trifluoroacetic Acid SCHEMBL4408071 0.83 TPSAB1 (0.59) F10TPSAB1
Trifluoroacetic Acid SCHEMBL4398566 0.83 TPSAB1 (0.55) F10TPSAB1
Hydrochloric Acid SCHEMBL4399035 0.82 TPSAB1 (0.54) F10TPSAB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1296972-B1 ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS AVENTIS PHARMA INC (US) 2009-12-23 EP disclosed
US-20050228018-A1 Chemical compounds AVENTIS PHARMACEUTICALS INC. (US) 2005-10-13 US disclosed
EP-1296972-A1 ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS Aventis Pharmaceuticals Inc. (US) 2003-04-02 EP disclosed
WO-2001090101-A1 ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS AVENTIS PHARMACEUTICALS INC. (US) 2001-11-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050228018-A1 Chemical compounds CMA1, TPSB2, TPSG1 F10 1734/4885TPSAB1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.