SCHEMBL4398712

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4400534	0.78	KCNN4 (0.36)	TAAR1CYP2C19HIF1AMAPTKMT2A
	SCHEMBL4937013	0.76	TAAR1 (0.56)	TAAR1KCNN4KIF11
	SCHEMBL15279067	0.75	ALDH1A1 (0.34)	CYP2C19HIF1AMAPTKCNN4
	SCHEMBL18380911	0.74	CYP2C19 (0.41)	TAAR1CYP2C19HIF1AKCNN4KIF11
	SCHEMBL28864314	0.74	TAAR1 (0.50)	TAAR1CYP2C19HIF1AMAPTKMT2A
	SCHEMBL11055846	0.74	CYP2C19 (0.48)	TAAR1CYP2C19HIF1AKMT2AMEN1
	SCHEMBL2064836	0.73	TAAR1 (0.48)	TAAR1CYP2C19MAPTKMT2AKCNN4
	SCHEMBL27684700	0.73	TAAR1 (0.48)	TAAR1KCNN4KIF11
	SCHEMBL2086206	0.73	TAAR1 (0.54)	TAAR1KCNN4KIF11
	SCHEMBL16213396	0.72	TAAR1 (0.44)	TAAR1CYP2C19MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.