Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 7/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16707821 | 0.83 | ALDH1A1 (0.41) | TAAR1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL20362568 | 0.79 | TSHR (0.38) | TAAR1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL16213117 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TSHRKMT2AMEN1L3MBTL1 | |
| SCHEMBL4937013 | 0.75 | TAAR1 (0.56) | TAAR1ALDH1A1TSHRKIF11 | |
| SCHEMBL16213089 | 0.75 | ALDH1A1 (0.46) | TAAR1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL1220936 | 0.75 | HTT (0.50) | TAAR1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL17651676 | 0.74 | MEN1 (0.49) | ALDH1A1KMT2AMEN1L3MBTL1HTT | |
| SCHEMBL4398712 | 0.72 | TAAR1 (0.45) | TAAR1KMT2AMEN1KIF11MAPT | |
| SCHEMBL4699693 | 0.72 | ALDH1A1 (0.44) | TAAR1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL2064836 | 0.71 | TAAR1 (0.48) | TAAR1TSHRKMT2AKIF11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017441-B2 | Direct anti-markovnikov addition of acids to alkenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2018-07-10 | — | — | US | disclosed |
| US-10017441-B2 | Direct anti-markovnikov addition of acids to alkenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2018-07-10 | — | — | US | disclosed |
| US-10017441-B2 | Direct anti-markovnikov addition of acids to alkenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2018-07-10 | — | — | US | disclosed |
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | UNIV NORTH CAROLINA (US) | 2016-04-07 | — | — | US | disclosed |
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | UNIV NORTH CAROLINA (US) | 2016-04-07 | — | — | US | disclosed |
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | UNIV NORTH CAROLINA (US) | 2016-04-07 | — | — | US | disclosed |
| WO-2014179648-A2 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-11-06 | — | — | WO | disclosed |
| WO-2014179648-A2 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096791-A1 | DIRECT ANTI-MARKOVNIKOV ADDITION OF ACIDS TO ALKENES | HAO2, DUOX2, PDK2 | TAAR1 3798/4885ALDH1A1 487/4885TSHR 4706/4885 |
| US-10017441-B2 | Direct anti-markovnikov addition of acids to alkenes | HAO2, DUOX2, PDK2 | TAAR1 3798/4885ALDH1A1 487/4885TSHR 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.