Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15670207 | 0.89 | KCNN4 (0.44) | CA2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL15670884 | 0.82 | GRM5 (0.37) | CA2MAPTMEN1KMT2AKCNN4 | |
| SCHEMBL15670885 | 0.82 | GRM5 (0.37) | CA2MAPTMEN1KMT2AKCNN4 | |
| SCHEMBL15670552 | 0.79 | KCNN4 (0.37) | CA2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15670551 | 0.79 | KCNN4 (0.37) | CA2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2366727 | 0.76 | CA2 (0.42) | CA2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30812516 | 0.76 | CRHBP (0.38) | CA2MEN1KMT2AALDH1A1CFTR | |
| SCHEMBL5872391 | 0.76 | CRHBP (0.38) | CA2MEN1KMT2AALDH1A1CFTR | |
| SCHEMBL5872386 | 0.76 | CRHBP (0.38) | CA2MEN1KMT2AALDH1A1CFTR | |
| SCHEMBL1443388 | 0.76 | CA2 (0.42) | CA2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178665-B2 | Process for the production of ezetimibe and intermediates used in this process | RICHTER GEDEON NYRT. (HU) | 2012-05-15 | — | — | US | disclosed |
| US-8178665-B2 | Process for the production of ezetimibe and intermediates used in this process | RICHTER GEDEON NYRT. (HU) | 2012-05-15 | — | — | US | disclosed |
| US-20090216009-A1 | PROCESS FOR THE PRODUCTION OF EZETIMIBE AND INTERMEDIATES USED IN THIS PROCESS | RICHTER GEDEON NYRT. (HU) | 2009-08-27 | — | — | US | disclosed |
| US-20090216009-A1 | PROCESS FOR THE PRODUCTION OF EZETIMIBE AND INTERMEDIATES USED IN THIS PROCESS | RICHTER GEDEON NYRT. (HU) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090216009-A1 | PROCESS FOR THE PRODUCTION OF EZETIMIBE AND INTERMEDIATES USED IN THIS PROCESS | APOB, HMGCR, PCSK9 | CA2 3417/4885MAPT 3554/4885MEN1 2791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.