Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14449133 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KMT2ARAB9AHSD17B10POLB | |
| SCHEMBL21895667 | 0.85 | ALDH1A1 (0.68) | ALDH1A1KMT2ARAB9AHSD17B10POLB | |
| SCHEMBL10388301 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KMT2ARAB9AHSD17B10POLB | |
| SCHEMBL13897067 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KMT2ARAB9AHSD17B10POLB | |
| SCHEMBL14213298 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KMT2ARAB9AHSD17B10POLB | |
| SCHEMBL4398747 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KMT2ARAB9AHSD17B10POLB | |
| SCHEMBL3197540 | 0.83 | KDM4E (0.45) | ALDH1A1KMT2ARAB9APOLBHPGD | |
| SCHEMBL10524520 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KMT2ARAB9AHSD17B10POLB | |
| SCHEMBL10023872 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KMT2ARAB9AHSD17B10POLB | |
| SCHEMBL19729141 | 0.81 | HTT (0.52) | ALDH1A1KMT2APOLBHPGDAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094760-B1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES CO (US) | 2017-05-31 | — | — | EP | disclosed |
| US-8431625-B2 | Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| US-8178604-B2 | Solid materials obtainable by ring-opening metathesis polymerization | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178604-B2 | Solid materials obtainable by ring-opening metathesis polymerization | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-05-15 | — | — | US | disclosed |
| EP-1815838-B1 | Solid materials obtainable by the ring-opening methathesis polymerization | 3M INNOVATIVE PROPERTIES CO (US) | 2010-09-08 | — | — | EP | disclosed |
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY | 2010-02-11 | — | — | US | disclosed |
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY | 2010-02-11 | — | — | US | disclosed |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY | 2009-04-02 | — | — | US | disclosed |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY | 2009-04-02 | — | — | US | disclosed |
| EP-1942125-A1 | Compositions curable by ring opening metathesis polymerarization at low temperatures and their application in the dental field | 3M Innovative Properties Company (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2008077001-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-06-26 | — | — | WO | disclosed |
| WO-2007089801-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | DNMT3B, HMBS, MMAB | ALDH1A1 454/4885KMT2A 1341/4885RAB9A 1469/4885 |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | MMAB, DNMT3B, RHEB | ALDH1A1 4132/4885KMT2A 1609/4885RAB9A 926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.