Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.45 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.45 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.45 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 11/20 | 0.44 |
| ▸ | CDC25B | P30305 | 8/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28411979 | 0.85 | SSTR1 (0.47) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL14590071 | 0.83 | SLC5A2 (0.44) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL19189070 | 0.82 | HTR1A (0.51) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL19189222 | 0.82 | HTR1A (0.51) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL14590072 | 0.81 | SSTR1 (0.42) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL14590067 | 0.81 | SSTR1 (0.44) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL5279710 | 0.81 | SSTR1 (0.44) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL5276770 | 0.81 | SSTR1 (0.44) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL673932 | 0.80 | SSTR1 (0.45) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL15610584 | 0.80 | SLC5A2 (0.42) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473671-B2 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2009-01-06 | — | — | US | disclosed |
| US-7331920-B2 | Glycopeptide antibiotics, combinational libraries of glycopeptide antibiotics and methods of producing same | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2008-02-19 | — | — | US | disclosed |
| US-20050075483-A1 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | TRUSTEES OF PRINCETON UNIVERSITY | 2005-04-07 | — | — | US | disclosed |
| US-20040106772-A1 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | TRUSTEES OF PRINCETON UNIVERSITY, THE | 2004-06-03 | — | — | US | disclosed |
| US-6710168-B1 | VANCOMYCIN DERIVATIVES | THE TRUSTEES OF THE UNIVERSITY OF PRINCETON | 2004-03-23 | — | — | US | disclosed |
| EP-1095058-A4 | GLYCOPEPTIDE ANTIBIOTICS, COMBINATORIAL LIBRARIES OF GLYCOPEPTIDE ANTIBIOTICS AND METHODS OF PRODUCING SAME | UNIV PRINCETON (US) | 2003-07-16 | — | — | EP | disclosed |
| EP-1179011-A1 | GLYCOPEPTIDE ANTIBIOTICS, COMBINATORIAL LIBRARIES OF GLYCOPEPTIDE ANTIBIOTICS AND METHODS OF PRODUCING SAME | Princeton University (US) | 2002-02-13 | — | — | EP | disclosed |
| EP-1095058-A1 | GLYCOPEPTIDE ANTIBIOTICS, COMBINATORIAL LIBRARIES OF GLYCOPEPTIDE ANTIBIOTICS AND METHODS OF PRODUCING SAME | Princeton University (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000069892-A1 | GLYCOPEPTIDE ANTIBIOTICS, COMBINATORIAL LIBRARIES OF GLYCOPEPTIDE ANTIBIOTICS AND METHODS OF PRODUCING SAME | PRINCETON UNIVERSITY (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000004044-A1 | GLYCOPEPTIDE ANTIBIOTICS, COMBINATORIAL LIBRARIES OF GLYCOPEPTIDE ANTIBIOTICS AND METHODS OF PRODUCING SAME | PRINCETON UNIVERSITY (US) | 2000-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106772-A1 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | NPR1, NPR3, OSTC | SSTR1 141/4885SSTR2 488/4885SSTR4 291/4885 |
| US-20050075483-A1 | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same | ARSA, STS, GARS1 | SSTR1 116/4885SSTR2 286/4885SSTR4 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.