Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4291540 | 0.86 | NPSR1 (0.54) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL4300220 | 0.78 | ALDH1A1 (0.52) | L3MBTL1ATMALDH1A1KDM4EHPGD | |
| SCHEMBL4296769 | 0.74 | L3MBTL1 (0.46) | L3MBTL1ATMALDH1A1KDM4EHPGD | |
| SCHEMBL4298023 | 0.70 | ALDH1A1 (0.59) | L3MBTL1ATMALDH1A1KDM4EHPGD | |
| SCHEMBL23928571 | 0.69 | L3MBTL1 (0.61) | L3MBTL1ATMALDH1A1KDM4EHPGD | |
| SCHEMBL4302539 | 0.69 | L3MBTL1 (0.62) | L3MBTL1ATMALDH1A1KDM4EHPGD | |
| SCHEMBL3833234 | 0.69 | HTR2C (0.45) | ALDH1A1SMN1; SMN2LMNAPOLBNPC1 | |
| SCHEMBL68334 | 0.68 | ALDH1A1 (0.58) | L3MBTL1ATMALDH1A1KDM4EHPGD | |
| SCHEMBL4698487 | 0.68 | ALDH1A1 (0.58) | L3MBTL1ATMALDH1A1KDM4EHPGD | |
| SCHEMBL18134651 | 0.68 | ALDH1A1 (0.48) | L3MBTL1ATMALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044055-A2 | AMIDE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008011131-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |