SCHEMBL68334

SCHEMBL68334

O=C(O)c1cn(-c2ccccc2)nc1C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
L3MBTL1 Q9Y468 4/20 0.58
HPGD P15428 3/20 0.58
KDM4E B2RXH2 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
HSD17B10 Q99714 1/20 0.58
CYP2C9 P11712 1/20 0.57
NPSR1 Q6W5P4 1/20 0.53
MAPT P10636 4/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
POLB P06746 2/20 0.52
USP2 O75604 1/20 0.52
RECQL P46063 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ATM Q13315 1/20 0.52
GAA P10253 1/20 0.51
AURKA O14965 2/20 0.51
TP53 P04637 1/20 0.51
HTT P42858 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29050843 0.89 ALDH1A1 (0.51) ALDH1A1L3MBTL1HPGDKDM4ESMN1; SMN2
SCHEMBL31665904 0.86 KMT2A (0.50) ALDH1A1L3MBTL1HPGDKDM4ESMN1; SMN2
SCHEMBL14821628 0.81 ALDH1A1 (0.69) ALDH1A1L3MBTL1HPGDKDM4ESMN1; SMN2
SCHEMBL4698487 0.81 ALDH1A1 (0.58) ALDH1A1L3MBTL1HPGDKDM4ESMN1; SMN2
SCHEMBL4298023 0.80 ALDH1A1 (0.59) ALDH1A1L3MBTL1HPGDKDM4ESMN1; SMN2
SCHEMBL22209187 0.80 ALDH1A1 (0.56) ALDH1A1L3MBTL1HPGDKDM4ESMN1; SMN2
SCHEMBL20366997 0.80 CYP2C9 (0.56) ALDH1A1L3MBTL1HPGDKDM4ESMN1; SMN2
SCHEMBL2830145 0.80 ALDH1A1 (0.56) ALDH1A1L3MBTL1HPGDKDM4ESMN1; SMN2
SCHEMBL4302959 0.80 CYP2C9 (0.56) ALDH1A1L3MBTL1HPGDKDM4ESMN1; SMN2
SCHEMBL4501557 0.79 ALDH1A1 (0.82) ALDH1A1L3MBTL1HPGDKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-5902709-A BRANCHED POLYESTER HAVING SPECIFIED TETRAHYDROFURAN-INSOUBLE CONTENT, MOLECULAR WEIGHT DISTRIBUTION TOMOEGAWA PAPER CO., LTD. (JP) 1999-05-11 US disclosed
US-5830979-A LOW MOLECULAR WEIGHT, POLYCARBOXYLIC ACID OR POLYALCOHOL HAVING AT LEAST 3 GROUPS TOMOEGAWA PAPER CO., LTD. (JP) 1998-11-03 US disclosed
US-5738965-A HAVING SPECIFIED POLYESTER BINDER RESIN TOMOEGAWA PAPER CO., LTD. (JP) 1998-04-14 US disclosed
US-5587265-A BLEND OF A COLORANT AND POLYESTER BINDER TOMOEGAWA PAPER CO., LTD. (JP) 1996-12-24 US disclosed
US-5565292-A LOW TEMPERATURE FIRING; BLEND OF COLORANT AND MODIFIED POLYESTER TOMOEGAWA PAPER CO., LTD. (JP) 1996-10-15 US disclosed
US-5466553-A Phenolic hydroxyl group-containing polyester binder resin TOMOEGAWA PAPER CO., LTD. (JP) 1995-11-14 US disclosed
US-5447814-A Electrostatic images with low temperature fixing properties TOMOEGAWA PAPER CO., LTD. (JP) 1995-09-05 US disclosed
EP-0655656-A1 Toner for developing electrostatic image TOMOEGAWA PAPER CO. LTD. (JP) 1995-05-31 EP disclosed
EP-0617337-A2 Toner for developing electrostatic image TOMOEGAWA PAPER CO. LTD. (JP) 1994-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 ALDH1A1 1901/4885L3MBTL1 4778/4885HPGD 311/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA ALDH1A1 1510/4885L3MBTL1 4438/4885HPGD 826/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA ALDH1A1 448/4885L3MBTL1 3440/4885HPGD 2278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.