SCHEMBL4399474

SCHEMBL4399474

COc1ccc(SOS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.50
BCHE P06276 1/20 0.50
PKM P14618 1/20 0.47
ALDH1A1 P00352 5/20 0.47
FFAR4 Q5NUL3 3/20 0.45
GABRG2 P18507 1/20 0.45
GABRB3 P28472 1/20 0.45
GABRA3 P34903 1/20 0.45
RAPGEF4 Q8WZA2 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPT P10636 2/20 0.43
DNMT1 P26358 1/20 0.43
HPGD P15428 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
EGFR P00533 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23241350 0.90 DNMT1 (0.52) PKMALDH1A1FFAR4MEN1KMT2A
SCHEMBL4390753 0.85 HTT (0.46) PKMALDH1A1EGFRLMNA
SCHEMBL14894834 0.79 BCHE (0.49) ACHEBCHEALDH1A1MEN1KMT2A
SCHEMBL7141187 0.79 KMT2A (0.44) ALDH1A1MEN1KMT2AMAPTDNMT1
SCHEMBL6938753 0.78 HTT (0.60) ACHEBCHEPKMALDH1A1MEN1
SCHEMBL10413156 0.78 HTT (0.60) ACHEBCHEPKMALDH1A1MEN1
SCHEMBL28736687 0.78 PKM (0.45) PKMALDH1A1MAPTHPGDCYP1A2
Iodide SCHEMBL9733834 0.76 HTT (0.58) ACHEBCHEPKMALDH1A1MEN1
SCHEMBL13665511 0.75 PKM (0.83) ACHEBCHEPKMALDH1A1RAPGEF4
SCHEMBL825670 0.75 PKM (0.83) ACHEBCHEPKMALDH1A1RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1238972-B1 Novel carbazole derivative and chemically amplified radiation-sensitive resin composition JSR CORP (JP) 2009-12-16 EP disclosed
EP-1238972-A1 Novel carbazole derivative and chemically amplified radiation-sensitive resin composition JSR Corporation (JP) 2002-09-11 EP disclosed