Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23241350 | 0.88 | DNMT1 (0.52) | KMT2ALMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL4399474 | 0.79 | ACHE (0.50) | KMT2ALMNAALDH1A1DNMT1MEN1 | |
| SCHEMBL14894834 | 0.78 | BCHE (0.49) | KMT2ANPC1LMNASMN1; SMN2HTT | |
| SCHEMBL7141184 | 0.74 | ALDH1A1 (0.39) | KMT2ALMNASMN1; SMN2HTTPTGS2 | |
| SCHEMBL9435856 | 0.74 | GAA (0.52) | KMT2ALMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6937180 | 0.74 | KMT2A (0.55) | KMT2ANPC1LMNASMN1; SMN2HTT | |
| SCHEMBL7140573 | 0.73 | ALDH1A1 (0.49) | KMT2ANPC1LMNASMN1; SMN2HTT | |
| SCHEMBL11587905 | 0.72 | GAA (0.50) | KMT2ALMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL7102153 | 0.71 | RAPGEF4 (0.53) | KMT2ADNMT1GAAVDRCA12 | |
| SCHEMBL10605735 | 0.70 | GAA (0.73) | KMT2ANPC1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086124-B1 | NOVEL CYCLOSPORINS | CHEM AG C (CH) | 2003-11-19 | — | — | EP | disclosed |
| US-6583265-B1 | Compound for use in the prevention of viral and bacterial infections | C-CHEM AG (CH) | 2003-06-24 | — | — | US | disclosed |
| EP-1086124-A1 | NOVEL CYCLOSPORINS | C-Chem AG (CH) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065933-A1 | NOVEL CYCLOSPORINS | C-CHEM AG (CH) | 1999-12-23 | — | — | WO | disclosed |