Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 10/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 10/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.48 |
| ▸ | PRKCG | P05129 | 3/20 | 0.48 |
| ▸ | PRKCB | P05771 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | PRKCA | P17252 | 3/20 | 0.48 |
| ▸ | PRKCH | P24723 | 3/20 | 0.48 |
| ▸ | PRKCI | P41743 | 3/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.48 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | PRKACA | P17612 | 2/20 | 0.48 |
| ▸ | PRKACG | P22612 | 2/20 | 0.48 |
| ▸ | PRKACB | P22694 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142951 | 0.90 | HTR6 (0.62) | HTR6ROCK2ROCK1PRKD3PRKCG | |
| SCHEMBL3156809 | 0.90 | HTR6 (0.62) | HTR6ROCK2ROCK1PRKD3PRKCG | |
| SCHEMBL3152855 | 0.89 | HTR6 (0.78) | HTR6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4397292 | 0.89 | HTR6 (0.61) | HTR6ROCK2ROCK1PRKD3PRKCG | |
| SCHEMBL3157039 | 0.88 | HTR6 (0.80) | HTR6ROCK2ROCK1PRKD3PRKCG | |
| SCHEMBL5818142 | 0.84 | ROCK2 (0.55) | HTR6ROCK2ROCK1PRKD3PRKCG | |
| SCHEMBL3152545 | 0.84 | HTR6 (0.78) | HTR6EPHX2SMN1; SMN2 | |
| SCHEMBL3156052 | 0.84 | HTR6 (0.80) | HTR6ROCK2ROCK1PRKD3PRKCG | |
| SCHEMBL3142862 | 0.83 | HTR6 (0.64) | HTR6 | |
| SCHEMBL3138523 | 0.83 | HTR6 (0.62) | HTR6CYP3A4CYP1A2CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |