Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15891156 | 0.82 | UBE2T (0.67) | ALDH1A1HSD17B10AOC3KMT2ARAB9A | |
| SCHEMBL1742930 | 0.80 | HRH3 (0.49) | HDAC4UBE2THRH3 | |
| SCHEMBL3554426 | 0.78 | UBE2T (0.48) | ALDH1A1HSD17B10L3MBTL1KMT2ARAB9A | |
| SCHEMBL4402275 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HSD17B10GAAKMT2AHDAC6 | |
| SCHEMBL30434376 | 0.77 | AKR1C3 (0.66) | ALDH1A1HSD17B10L3MBTL1GAAAOC3 | |
| SCHEMBL1433065 | 0.77 | AKR1C3 (0.66) | ALDH1A1HSD17B10L3MBTL1GAAAOC3 | |
| SCHEMBL1630859 | 0.76 | L3MBTL1 (0.58) | ALDH1A1HSD17B10L3MBTL1GAAAOC3 | |
| SCHEMBL29576128 | 0.76 | ME2 (0.60) | ALDH1A1HSD17B10L3MBTL1GAAAOC3 | |
| SCHEMBL23245953 | 0.75 | SYK (0.53) | ALDH1A1HSD17B10L3MBTL1GAAAOC3 | |
| SCHEMBL29618450 | 0.75 | SYK (0.53) | ALDH1A1HSD17B10L3MBTL1GAAAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959951-B1 | HETEROARYL SUBSTITUTED PIPERIDINE DERIVATIVES AS L-CPT1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-12-23 | — | — | EP | disclosed |