Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 10/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 10/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824244 | 0.86 | KDM4E (0.47) | PDGFRBPDGFRAKDM4EPIK3CDPIK3CA | |
| SCHEMBL16223776 | 0.72 | ALDH1A1 (0.36) | KDM4EEGFRMAPTALDH1A1CYP3A4 | |
| SCHEMBL4402445 | 0.72 | CYP2A6 (0.34) | CYP1A2CYP2C19KMT2ACYP2A6 | |
| SCHEMBL2346887 | 0.72 | PDGFRB (1.00) | PDGFRBPDGFRAKDM4EEGFRPIK3CD | |
| SCHEMBL4401093 | 0.72 | CYP2A6 (0.34) | KDM4EL3MBTL1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2889003 | 0.72 | CYP1A2 (0.50) | KDM4EALDH1A1CYP1A2KMT2ACYP2A6 | |
| SCHEMBL4397412 | 0.72 | CYP1A2 (0.34) | NPC1L3MBTL1CYP1A2CYP2A6 | |
| SCHEMBL23954144 | 0.69 | KDM4E (0.66) | PDGFRBPDGFRAKDM4EEGFRPIK3CD | |
| SCHEMBL10321126 | 0.68 | CYP1A2 (0.41) | EGFRNPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL19695 | 0.68 | TSHR (0.42) | KDM4ENPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817309-B1 | ACETAMIDE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-12-23 | — | — | EP | claimed |