SCHEMBL4400137

SCHEMBL4400137

COc1cc(-c2cc(OC)c(O)cc2OC)c(OC)cc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.50
ACHE P22303 2/20 0.48
MAOA P21397 3/20 0.47
PTGS2 P35354 1/20 0.47
HTT P42858 1/20 0.45
CYP3A4 P08684 2/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
RECQL P46063 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TNFSF11 O14788 1/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
SLC22A8 Q8TCC7 1/20 0.43
MEN1 O00255 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
HMGCR P04035 1/20 0.43
CA1 P00915 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69624 0.89 MAOB (0.59) MAOBHTTCYP3A4MAPTHPGD
SCHEMBL11233383 0.83 MAOB (0.54) MAOBHTTCYP3A4MAPTHPGD
SCHEMBL1402467 0.83 MAOB (0.54) MAOBHTTCYP3A4MAPTHPGD
SCHEMBL19361333 0.80 ALOX5 (0.48) MAOBPTGS2
SCHEMBL19437875 0.78 ACHE (0.53) MAOBACHECYP3A4HPGDKDM4E
SCHEMBL1987450 0.77 HTT (0.58) MAOBACHEPTGS2HTTCYP3A4
SCHEMBL30648558 0.77 HTT (0.58) MAOBACHEPTGS2HTTCYP3A4
SCHEMBL18040253 0.77 TNFSF11 (0.56) ACHEMAOAHTTCYP3A4MAPT
SCHEMBL29421892 0.77 MAOB (0.48) MAOBMAOAHTTCYP3A4MAPT
SCHEMBL70697 0.77 CYP3A4 (0.50) MAOBMAOAHTTCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9023974-B2 Ester group-containing tetracarboxylic acid dianhydride, novel polyesterimide precursor derived therefrom, and polyesterimide HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2015-05-05 US disclosed
US-20090306329-A1 NOVEL ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, NOVEL POLYESTERIMIDE PRECURSOR DERIVED THEREFROM, AND POLYESTERIMIDE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306329-A1 NOVEL ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, NOVEL POLYESTERIMIDE PRECURSOR DERIVED THEREFROM, AND POLYESTERIMIDE NOTUM, WEE2, THEM6 MAOB 4536/4885ACHE 4620/4885MAOA 4023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.