Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398065 | 0.86 | ITGA4 (1.00) | ITGA4ITGB1 | |
| SCHEMBL4398074 | 0.86 | ITGA4 (1.00) | ITGA4ITGB1 | |
| SCHEMBL5987573 | 0.84 | ITGA4 (1.00) | ITGA4ITGB1 | |
| Trifluoroacetic Acid SCHEMBL4395775 | 0.83 | ITGA4 (0.94) | ITGA4ITGB1 | |
| Trifluoroacetic Acid SCHEMBL4395768 | 0.83 | ITGA4 (0.94) | ITGA4ITGB1 | |
| SCHEMBL13884450 | 0.81 | ITGA4 (0.85) | ITGA4ITGB1 | |
| SCHEMBL4393458 | 0.81 | ITGA4 (1.00) | ITGA4ITGB1 | |
| SCHEMBL4393455 | 0.81 | ITGA4 (1.00) | ITGA4ITGB1 | |
| SCHEMBL4395640 | 0.81 | ITGA4 (1.00) | ITGA4ITGB1 | |
| SCHEMBL4395630 | 0.81 | ITGA4 (1.00) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514409-B2 | VLA-4 antagonists | MERCK & CO., INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-20070179190-A1 | Vla-4 antagonists | MERCK & CO., INC. (US) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179190-A1 | Vla-4 antagonists | VCAM1, ITGA4, ITGB4 | ITGA4 2/4885ITGB1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.