SCHEMBL4400260

SCHEMBL4400260

c1ccc2c(c1)c1ccccc1n2-c1ccc(-c2cnc(-n3c4ccccc4c4ccccc43)cn2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 2/20 0.47
ATM Q13315 1/20 0.47
HDAC4 P56524 1/20 0.36
CHRNA7 P36544 1/20 0.35
KCNH2 Q12809 1/20 0.35
PTPN1 P18031 2/20 0.32
KMT2A Q03164 2/20 0.31
IL1R1 P14778 1/20 0.31
MKNK1 Q9BUB5 1/20 0.31
MKNK2 Q9HBH9 1/20 0.31
HTT P42858 3/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
ATR Q13535 1/20 0.31
AOC3 Q16853 1/20 0.31
MEN1 O00255 1/20 0.31
OXTR P30559 1/20 0.30
AVPR1A P37288 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22747709 0.98 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4CHRNA7
SCHEMBL8400356 0.92 KDM4E (0.55) L3MBTL1KDM4EATMHDAC4PTPN1
SCHEMBL15073490 0.84 L3MBTL1 (0.45) L3MBTL1KDM4EATMCHRNA7KCNH2
SCHEMBL15073526 0.84 L3MBTL1 (0.45) L3MBTL1KDM4EATMCHRNA7KCNH2
SCHEMBL13141860 0.83 KDM4E (0.46) L3MBTL1KDM4EATMHDAC4PTPN1
SCHEMBL15073782 0.82 L3MBTL1 (0.42) L3MBTL1KDM4EATMCHRNA7KCNH2
SCHEMBL4400259 0.82 KDM4E (0.52) L3MBTL1KDM4EATMHDAC4CHRNA7
SCHEMBL613059 0.82 KDM4E (0.52) L3MBTL1KDM4EATMHDAC4CHRNA7
SCHEMBL19654622 0.82 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL19654640 0.82 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2141152-B1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2021-05-05 EP disclosed
US-RE46368-E1 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2017-04-18 US disclosed
US-RE46368-E1 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2017-04-18 US disclosed
EP-1858094-B1 ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE PIONEER CORP (JP) 2017-03-08 EP disclosed
EP-1829871-B1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT PIONEER CORP (JP) 2015-08-12 EP disclosed
US-8911886-B2 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-12-16 US disclosed
US-8911886-B2 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-12-16 US disclosed
US-20140159023-A1 ORGANIC EL MULTI-COLOR LIGHT-EMITTING DEVICE Idemitsu Co., Ltd. (JP) 2014-06-12 US disclosed
US-20140159023-A1 ORGANIC EL MULTI-COLOR LIGHT-EMITTING DEVICE Idemitsu Co., Ltd. (JP) 2014-06-12 US disclosed
US-8580398-B2 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-11-12 US disclosed
US-20090236973-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT PIONEER CORPORATION (JO) 2009-09-24 US disclosed
US-20090236973-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT PIONEER CORPORATION (JO) 2009-09-24 US disclosed
US-20090191426-A2 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT PIONEER CORPORATION (JP) 2009-07-30 US disclosed
US-20090191426-A2 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT PIONEER CORPORATION (JP) 2009-07-30 US disclosed
US-20090021146-A1 ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE PIONEER CORPORATION (JP) 2009-01-22 US disclosed
US-20090021146-A1 ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE PIONEER CORPORATION (JP) 2009-01-22 US disclosed
US-20080145699-A1 Organic Compound, Charge-Transporting Material, and Organic Electroluminescent Element PIONEER CORPORATION (JP) 2008-06-19 US disclosed
US-20080145699-A1 Organic Compound, Charge-Transporting Material, and Organic Electroluminescent Element PIONEER CORPORATION (JP) 2008-06-19 US disclosed
EP-1829871-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT Pioneer Corporation (JP) 2007-09-05 EP disclosed
EP-1820801-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT Pioneer Corporation (JP) 2007-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090021146-A1 ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE SLC25A21, SLCO2A1, OCIAD2 L3MBTL1 690/4885KDM4E 2880/4885ATM 4296/4885
US-20090191426-A2 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLC39A3, SLCO2A1, SLC39A11 L3MBTL1 1312/4885KDM4E 3607/4885ATM 3886/4885
US-20090236973-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLCO4C1, SLCO2A1, SLCO2B1 L3MBTL1 702/4885KDM4E 2187/4885ATM 4266/4885
US-20080145699-A1 Organic Compound, Charge-Transporting Material, and Organic Electroluminescent Element SLC39A3, SLCO2A1, SLC39A11 L3MBTL1 1312/4885KDM4E 3607/4885ATM 3886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.