SCHEMBL4400259

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL613059	0.93	KDM4E (0.52)	KDM4EATML3MBTL1CHRNB2CHRNA7
	SCHEMBL15421256	0.93	KDM4E (0.52)	KDM4EATML3MBTL1CHRNB2CHRNA7
	SCHEMBL13100546	0.92	KDM4E (0.50)	KDM4EATML3MBTL1CHRNB2CHRNA7
	SCHEMBL13866634	0.90	MAOA (0.44)	KDM4EATML3MBTL1CHRNB2CHRNA7
	SCHEMBL8400356	0.89	KDM4E (0.55)	KDM4EATML3MBTL1HDAC4PTPN1
	SCHEMBL4402531	0.89	KDM4E (0.54)	KDM4EATML3MBTL1CHRNB2CHRNA7
	SCHEMBL29549947	0.89	KDM4E (0.54)	KDM4EATML3MBTL1CHRNB2CHRNA7
	SCHEMBL12524852	0.89	L3MBTL1 (0.52)	KDM4EATML3MBTL1CHRNB2CHRNA7
	SCHEMBL24041704	0.89	L3MBTL1 (0.45)	KDM4EATML3MBTL1CHRNB2CHRNA7
	SCHEMBL16089825	0.88	KDM4E (0.40)	KDM4EATML3MBTL1CHRNB2CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.