SCHEMBL8400356

SCHEMBL8400356

c1ccc2c(c1)c1ccccc1n2-c1ccc(-c2cnc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)cn2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
ATM Q13315 1/20 0.55
HDAC4 P56524 1/20 0.40
PTPN1 P18031 2/20 0.35
KMT2A Q03164 3/20 0.35
IL1R1 P14778 1/20 0.35
GPR3 P46089 1/20 0.34
HTT P42858 3/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ATR Q13535 1/20 0.33
PTK2B Q14289 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4400260 0.92 L3MBTL1 (0.47) KDM4EL3MBTL1ATMHDAC4PTPN1
SCHEMBL22747709 0.91 L3MBTL1 (0.46) KDM4EL3MBTL1ATMHDAC4PTPN1
SCHEMBL13141860 0.91 KDM4E (0.46) KDM4EL3MBTL1ATMHDAC4PTPN1
SCHEMBL613059 0.89 KDM4E (0.52) KDM4EL3MBTL1ATMHDAC4PTPN1
SCHEMBL4400259 0.89 KDM4E (0.52) KDM4EL3MBTL1ATMHDAC4PTPN1
SCHEMBL19654640 0.89 L3MBTL1 (0.49) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL19654622 0.89 L3MBTL1 (0.49) KDM4EL3MBTL1ATMHDAC4KMT2A
SCHEMBL13100546 0.88 KDM4E (0.50) KDM4EL3MBTL1ATMHDAC4PTPN1
SCHEMBL10205989 0.87 L3MBTL1 (0.50) KDM4EL3MBTL1ATMHDAC4PTPN1
SCHEMBL17227970 0.87 KDM4E (0.42) KDM4EL3MBTL1ATMKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3389110-B1 ORGANIC ELECTROLUMINESCENT ELEMENT UDC IRELAND LTD (IE) 2023-12-27 EP disclosed
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 US disclosed
US-10651398-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2020-05-12 US disclosed
US-10629817-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2020-04-21 US disclosed
US-10431749-B2 Organic electroluminescent element UDC IRELAND LIMITED (IE) 2019-10-01 US disclosed
US-10276637-B2 Organic EL multi-color light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2019-04-30 US disclosed
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-01-29 US disclosed
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-01-17 US disclosed
US-20180145260-A1 MATERIALS FOR ORGANIC ELECTRLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-05-24 US disclosed
US-20180145260-A1 MATERIALS FOR ORGANIC ELECTRLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-05-24 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
WO-2011013859-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-02-03 WO disclosed
EP-2169028-A2 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same Idemitsu Kosan Co., Ltd. (JP) 2010-03-31 EP disclosed
US-20070257600-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-08 US disclosed
US-20070257600-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-08 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145260-A1 MATERIALS FOR ORGANIC ELECTRLUMINESCENT DEVICES KCNB2, KCNB1, GJB2 KDM4E 3737/4885L3MBTL1 2807/4885ATM 2814/4885
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, L1CAM, AGO2 KDM4E 3248/4885L3MBTL1 1678/4885ATM 2324/4885
US-10431749-B2 Organic electroluminescent element EML4, L1CAM, EPHA4 KDM4E 427/4885L3MBTL1 156/4885ATM 2840/4885
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L KDM4E 1058/4885L3MBTL1 1447/4885ATM 4497/4885
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same UQCRB, OXA1L, HBS1L KDM4E 984/4885L3MBTL1 1516/4885ATM 4547/4885
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element LEF1, L1CAM, AGO2 KDM4E 3248/4885L3MBTL1 1678/4885ATM 2324/4885
US-10629817-B2 Materials for organic electroluminescent devices KCNB2, KCNB1, GJB2 KDM4E 3816/4885L3MBTL1 2626/4885ATM 3054/4885
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same UQCRB, OXA1L, HBS1L KDM4E 984/4885L3MBTL1 1516/4885ATM 4547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.