Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403111 | 0.93 | ITGB3 (0.42) | ITGB3ITGA2BGPR119KMT2A | |
| SCHEMBL11918141 | 0.91 | ITGB3 (0.44) | ITGB3ITGA2BGPR119KMT2AHTR4 | |
| SCHEMBL12160436 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL12106843 | 0.84 | ITGB3 (0.44) | ITGB3ITGA2BHTR4 | |
| Hydrochloric Acid SCHEMBL1295876 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2B | |
| SCHEMBL1295258 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL12103493 | 0.82 | ITGB3 (0.53) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL11918183 | 0.82 | GPR119 (0.49) | ITGB3ITGA2BGPR119 | |
| SCHEMBL12106783 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL12106892 | 0.81 | ITGB3 (0.48) | ITGB3ITGA2BITGAVCHRM2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321308-B1 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-05-09 | — | — | EP | disclosed |