Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11918141 | 0.94 | ITGB3 (0.44) | ITGB3ITGA2BRAB9AGPR119KMT2A | |
| SCHEMBL4400660 | 0.93 | ITGB3 (0.43) | ITGB3ITGA2BGPR119KMT2A | |
| SCHEMBL11918183 | 0.89 | GPR119 (0.49) | ITGB3ITGA2BHPGDSRAB9AGPR119 | |
| SCHEMBL12160436 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL4403130 | 0.82 | GABRA5 (0.48) | ITGB3ITGA2BEGLN1HPGDSRAB9A | |
| SCHEMBL13534631 | 0.81 | GPR119 (0.62) | EGLN1HPGDSRAB9AGPR119FASN | |
| SCHEMBL12106843 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL2391570 | 0.81 | GPR119 (0.52) | EGLN1HPGDSGPR119FASN | |
| SCHEMBL2391566 | 0.81 | GPR119 (0.52) | EGLN1HPGDSGPR119FASN | |
| Hydrochloric Acid SCHEMBL1295876 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321308-B9 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-08-08 | — | — | EP | disclosed |
| EP-2321308-B1 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-05-09 | — | — | EP | disclosed |